Hi all, new here. I've been dealing with severe depression and bipolar issues since the death of my fiance' about a year and a half ago. I've struggled with depression on and off most of my life and was already taking Cymbalta but it seemed to stop working (or my depression became more severe, I'm not sure) so after a trip to the mental hospital on an outpatient basis and three different psychiatrists later, my current doctor kept me on the Cymbalta (60mgs) but added Seroquel, Geodon (for the bipolar) and Klonopin (to help me sleep and for anxiety as needed). However, I still have all the classic symptoms with depression and over the past couple of months it got much worse.
Last month he upped my Cymbalta to 90 mgs and while it seemed to help me mentally, my body just couldn't tolerate it. I was incredibly tired all the time and couldn't function so last week he dropped it back to 60mgs and added Wellbutrin XL (extended release, 75mg I believe). I take the Cymbalta in the pm along with my bipolar meds because they make me sleepy, and Wellbutrin in the morning along with my daily vitamins. I'm not noticing anything yet, and I forget how long it takes Wellbutrin to take effect.
Has anyone else taken Cymbalta with Wellbutrin, and did it work for you? Did the tiredness go away? I'm really hoping this cocktail of meds will do something, because I'm getting frusterated and more depressed since nothing seems to be helping. Thanks!
